Preservation of eggs: new knowledge of fertility in women

Preservation of eggs: new knowledge of fertility in women

durable proteins and fertility: a long connection

In a new study, the role of extremely durable proteins in the ovary is examined in the preservation of fertility of mammals, including humans. Research suggests that these proteins help keep egg cells healthy and thus ensure the possibility of long fertility. This fact could play a crucial role in understanding how the female body can keep its reproductive cells functional for decades.

One of the main knowledge from the experiments at the Max Planck Institute for Multidisciplinary Natural Sciences in Göttingen is that ovaries contain a large number of extremely durable proteins. Compared to other tissues and even the brain, ovaries have a higher concentration of these proteins. These proteins are not only present in the egg cells themselves, but also in other cells in the ovary.

The researchers around Melina Schuh, Juliane Liepe and Henning vacation have found that many of these long -lasting proteins have protein functions, such as the repair of DNA or the protection of the cells from damage. It is particularly interesting that chaperone, which are responsible for the correct folding of proteins, are more stable in the ovary than in others. This stability could help proteins remain functional for longer and protect the cell from damage.

The concentration of many durable proteins in the ovary decreases with age. At the same time, the amount of proteins that are connected to inflammation and an immune response increases. These changes in the protein network could explain why fertility in female mammals decreases in old age.

Research thus shows that extremely durable proteins in the ovary play an essential role in maintaining fertility. This knowledge could help find new ways to maintain or improve the fertility of women, also with regard to later phases of life.

- Nag